NFKB1 and Nephropathy: For example, Sancaktutar and coworkers [40] showed that pomegranate extract reduced histological and functional kidney damage in a model of renal ischaemia–reperfusion, while Mirhan et al. [41] demonstrated protection through inhibition of the NF-κB signalling pathway and reduction in oxidative stress, neutrophil infiltration, and pro-inflammatory cytokine release.