VAT and SAT were used to measure the gene expression of the VLDL receptor (VLDLR), lipoprotein lipase (LPL), acylation stimulating protein (ASP), LDL receptor-related protein 1 (LRP1), and fatty acid binding protein 4 (FABP4) in 28 morbidly obese patients with Type 2 Diabetes Mellitus (T2DM) or high IR, 10 morbidly obese patients with low IR, 10 obese patients with low IR, and 12 lean, healthy controls. The gene discussed is C3; the disease is type 2 diabetes mellitus.