AKT1 and Insulin resistance: These authors attempted to elucidate the antidiabetic mechanisms of Veratrilla baillonii extract and showed, by transcriptome analysis of the liver, that the treatment significantly suppressed the expression of many genes involved in insulin resistance and inhibited the levels of Foxo1, G6pc, c-Met and Pik3r1 in the liver while the expressions of genes related to metabolism and inflammation, including Sirt1, Irs1, Akt1, were significantly increased after treatment with Veratrilla baillonii extract.