Additionally, cyclin D1 (CCND1; chr 11q), fibroblast growth factor receptor 3 (FGFR3; chr 4p), and PIK3CA (chr 3q) were amplified in the tumor tissues from patients S390 and S425, S425 and S028, and S425 and S424, respectively. The gene discussed is FGFR3; the disease is neoplasm.