In contrast to tumor tissues, NATs did not show many gene amplifications, whereas deletions of X-chromosome genes such as lysine demethylase 5C (KDM5C), lysine demethylase 5C (KDM6A), ATRX chromatin remodeler (ATRX), and BCL6 corepressor (BCOR) were commonly observed. This evidence concerns the gene KDM5C and neoplasm.