In multivariate models including albumin-corrected calcium, regardless of how pituitary deficiencies were defined (presence/absence of hypopituitarism, panhypopituitarism, number of hormonal deficits, or specific hormonal deficits), age (OR 1.09, 95% CI 1.01–1.18, p = 0.02) and the presence of expansive lesions other than pituitary adenomas, craniopharyngiomas, and Rathke’s cleft cysts (OR 17.73 vs. pituitary adenoma, 95% CI 1.32–238.54, p = 0.03) emerged as independent predictors of prolonged QTc. The gene discussed is ALB; the disease is panhypopituitarism.