LPA and coronary artery disorder: In summary, while LDL-cholesterol concentrations remained consistently higher among STEMI patients irrespective of lipoprotein(a) levels, elevated Lp(a) was strongly associated with an increased burden of multivessel coronary artery disease, predominantly in the NSTEMI cohort, thereby highlighting its potential contributory role in the pathophysiology and progression of diffuse atherosclerotic disease (Table 2).