In one study, 2D-PAGE combined with MALDI analysis uncovered the overexpression of proteins, such as S100A9, in the BALF of patients with IPF, as compared to patients with other fibrotic diseases, highlighting the value of proteomics in identifying biomarkers capable of distinguishing among different types of fibrotic interstitial pneumonia [43]. The gene discussed is S100A9; the disease is idiopathic interstitial pneumonia.