In both the TCGA and CGGA GBM cohorts, high expressions of IGF2, RETN, C3AR1, CLCF1, NTRK1, OSMR, KCNN4, SLC18A3 and HTR7 predicted poorer prognoses, while EDNRB was correlated with a better outcome (Figure 3 and Figure 4). The gene discussed is RETN; the disease is glioblastoma.