CD4 and neoplasm: In contrast, CD4+ T cells and CD68+ macrophages exhibited distinct distribution patterns: the peak CT/IM ratio in OCRC was significantly higher than that in Non-obstructed CRC in T4 tumor (obstructed vs. non-obstructed: 1.04 vs. 0.71 for CD68; 0.92 vs. 0.47 for CD20), whereas no such difference was observed in the T1–3 tumor (obstructed vs. non-obstructed: 0.52 vs. 0.50 for CD68; 0.47 vs. 0.49 for CD4).