SNHG6 and neoplasm: In metabolic reprogramming, SNHG6 enhances glycolysis by stabilizing BOP1 [88], SNORA55 mediates TRPM8-induced nuclear-mitochondrial communication to regulate ATP synthase function [89], and SNORA14A suppresses succinate accumulation by upregulating SDHB, thereby slowing hepatoblastoma progression [90], emphasizing the link between metabolic imbalance and tumor energy adaptation.