TTR and amyloidosis: A variant in the gene TTR (encoding transthyretin, a homotetrameric protein whose function is to transport the thyroid hormone thyroxine and the retinol-binding protein bound to retinol, UniProt ID: P02766) (p.Ser72Pro) (associated with Amyloidosis, hereditary systemic 1-AMYLD1) affects a phosphorylated serine located in a flexible linker on the protein surface.