POU5F1 and non-small cell lung carcinoma: This suppression is mechanistically linked to NSCLC metastasis through miR-145’s targeting of key oncogenes involved in invasion (MMP9, FSCN1), stemness (OCT4, KLF4, c-Myc), and epithelial–mesenchymal transition (ZEB1/2, SNAIL, Vimentin) [20,22].