The expressions of growth hormone-releasing hormone (GHRH) and GHRH-SV1 (splice variant 1 SV1) were markeredly increased in the eutopic endometrium and ectopic lesions compared with normal endometrium, and were higher in advanced (stages III-IV) than in early (stage I-II) endometriosis [16]. This evidence concerns the gene GHRH and endometriosis.