Based on previous studies classifying the RBP family, we estimated the differential expressions of RBPs in pan-cancer using RNA sequencing data from the TCGA database, including RBP1, RBP2, RBP3, RBP4, RBP5, RBP7, RLBP1, CRABP1, and CRABP2. The gene discussed is RBP5; the disease is cancer.