CASP3 and breast cancer: MCF-7 BC cells were arrested at the G2/M phase and MDA-MB-231 BC cells at the S phase, and the expressions of caspase 3/9, Bcl2-associated protein and protein 53 were upregulated after treatment with Car-Nio, whereas those of microRNA-183, poly (ADP-ribose) polymerase and B-cell lymphoma 2 were downregulated [258].