An inverse correlation of kisspeptin 1 and kisspeptin 1 receptor expression in African American women suffering from triple-negative BC has been reported: kisspeptin 1 receptor was higher in non-triple-negative BC than in other groups; kisspeptin 1 protein expression was higher in receptor-negative and triple-negative BC than in other populations; kisspeptin 1 receptor was marginally negatively associated with tumor size but positively correlated with disease-free survival and lymph node positivity [119]. Here, KISS1 is linked to breast cancer.