Moreover, the various research conducted on lung cancer cell lines and clinical trials allowed us to link the dysregulated expression of cuproptosis-associated genes, such as genes coding ferredoxin 1 (FDX1), lipotransferase 1 (LIPT1), copper transporter 1 (CTR1), and ATPase copper-transporting α/β (ATP7A/B), to lung cancer progression. This evidence concerns the gene FDX1 and lung cancer.