SLC5A2 and acute kidney injury: The integration of risk-based prophylaxis, individualized post-contrast monitoring within 48–72 h, and emerging nephroprotective interventions—such as the endothelial and mitochondrial stabilization provided by SGLT2 inhibitors, Viggiano et al. (2025) may collectively enhance renal resilience and mitigate the burden of CA-AKI in high-risk populations [31].