In glomerulonephritides, including LN and IgAN, ncRNAs modulate interferon signaling, NF-κB activation, immune cell function, and podocyte stability, exemplified by lncRNA-p21, RP11-2B6.2, lnc-DC, and circHLA-C/miR-150 axes. The gene discussed is CDKN1A; the disease is lobular neoplasia.