PRF1 and Wolman disease: The genetic diversity of disease-causing FHL- (PRF1 {FHL-2}, UNC13D {FHL-3}, STXBP2 {FHL-5}) and HLH-related genes (SH2D1A, XIAP, RAB27a, ZNFX1), as well as clinically diagnosed diseases such as chronic granulomatous disease (CGD) and Wolman’s disease, in our cohort is depicted in Figure 2.