PADI4 and periodontitis: For example, Oliveira et al. [84] explored the association between SNPs of the peptidyl arginine deaminase type 4 (PADI4) gene and the GTG haplotype with rheumatoid arthritis (RA), periodontitis, and neutrophil extracellular traps (NETs) in vitro, and discovered that the release of NETs by circulating neutrophils is associated with RA and periodontitis and is influenced by the presence of the GTG haplotype.