PathCards highlighted high-score (> 11) disease associations concordant with the network structure, including follicular basal cell carcinoma (TSC2, RICTOR, RHEB, RPS6KB1, MTOR, MLST8, TSC1, RPTOR, EIF4EBP1, AKT1), childhood ovarian dysgerminoma (AKT1, EIF4EBP1, MLST8, TSC1, TSC2, RPS6KB1, RPTOR, MTOR, RHEB, RICTOR), and gastric adenocarcinoma (AKT1, MTOR, RAF1), mirroring the enrichment profile from STRING and the sub-modules inferred from GeneMANIA (Table 2). The gene discussed is RPTOR; the disease is gastric adenocarcinoma.