The panel of genes included PKD-related genes such as DNAJB11, DZIPL1L, GANAB, HNF1B, PKD1, PKD2, PKHD1, NOTCH2, PAX2, UMOD, BICC1, and PRKCSH, LRP5, SEC63, and GANAB-related polycystic liver disease (PCLD). Here, NOTCH2 is linked to Isolated polycystic liver disease.