Evodiamine alleviates oxidative stress and promotes corneal epithelial repair in dry eye disease by activating autophagy through the p53/mTOR pathway [66], while Salidroside reduces oxidative damage in dry eye by enhancing autophagy via the AMPK-Sirt1/Nrf2 axis [67]. The gene discussed is TP53; the disease is Keratoconjunctivitis sicca.