In addition, several cancer- and inflammation-related pathways were detected, including PD-L1/PD-1 checkpoint signaling, NF-κB signaling, lipid and atherosclerosis, regulation of the actin cytoskeleton, FcγR-mediated phagocytosis, and sphingolipid metabolism/signaling [28,30,31]. Here, CD274 is linked to atherosclerosis.