For example, in a patient with glaucoma who has experienced chronic optic nerve degeneration and loss of RGCs, stem cell therapies could be used to restore RGCs, along with methods for axon regeneration such as PTEN inhibition, supply of growth factors like oncomodulin, and an implant to generate an electric field from the proximal optic nerve to the LGN. Here, OCM is linked to glaucoma.