Several genes had PheWAS-coloc results (associated at P < 5 × 10−5 and colocalized at PPH4 > 0.8) for immune-mediated conditions beyond T1D, including primary sclerosing cholangitis (CLNK and NFKB1), myasthenia gravis (SESN3), Grave’s disease (CLNK and SESN3), rheumatoid arthritis (CLNK and SESN3), and asthma (EED, NFKB1, REST). The gene discussed is SESN3; the disease is type 1 diabetes mellitus.