In contrast, other variables—including sex, age, BMI, smoking status, DM, hypertension, cardiovascular disease, preoperative treatments, hemoglobin, albumin, Cr, GOT, GPT, approach type, stoma type (colostomy or ileostomy), stoma type (end or loop), use of the skin bridge method, base area of stoma, oblateness of stoma, and chemotherapy—were not significantly associated with the development of severe peristomal skin disorders during follow-up (all p > 0.05). The gene discussed is ALB; the disease is skin disorder.