TET2 and hepatocellular carcinoma: For instance, human menstrual blood-derived stem cells (MenSCs) enhance TET2 expression to reverse BCL-2-interacting protein 3 (BNIP3)/ BCL-2-interacting protein 3-like (BNIP3L) promoter hypermethylation in sorafenib-resistant HCC, thereby amplifying sorafenib-induced mitophagy and resistant-cell death [194].