NLRP3 and obstructive sleep apnea syndrome: Additionally, Zhu et al. [157] found that obstructive sleep apnea‐hypopnea syndrome (OSAHS) increases NLRP3 and caspase‐1 activation in periodontal tissues, making them more vulnerable to inflammatory lesions through the ROS/TXNIP/NLRP3 pathway [157].