A finer characterization of macrophage polarization states (e.g. M2a, M2b, M2c) and CD4+ T-helper subtypes (e.g. Th1, Th2, Th17, Treg), as well as the inclusion of additional cytokines such as TNF-α, IFN-γ, IL-17, and TGF-β, will be essential to provide a more comprehensive picture of immune remodeling in adenomyosis. Here, CD4 is linked to adenomyosis.