SPP1 and cervical cancer: for simultaneous detection of OPN and vascular endothelial growth factor (VEGF) using both colorimetric detection and SERS spectroscopy with LODs of 10 pg mL−1 and 0.8 pg mL−1, respectively.[280] Using plasma samples of healthy controls and cervical cancer patients, the authors demonstrated that the 15‐min diagnostic test sensitivity and specificity were 92% and 94%, respectively, making it a promising tool for the early detection of cervical cancer in point‐of‐care settings.