EPCAM and neoplasm: developed a novel biomimetic microfluidic system that integrates an aptamer specific to epithelial cell adhesion molecule (EpCAM) conjugated on functionalized iron‐oxide magnetic nanoclusters with a nickel‐patterned microfluidic device.[326] Using a magnetically controlled microfluidic chip, the nanoclusters formed an in‐flow capture matrix for CTCs, allowing rapid processing of whole blood samples and downstream fluorescent detection of over 90% of the rare tumor cells (e.g., down to five cells in the 20 μL sample volume) within 20 min.