Nevertheless, administration of CGA derived from Honeysuckle extract led to substantially reduced levels of CD8+ and CD4+ T cells relative to the ARDS cohort (p < 0.0001), while elevations in CD25 + Foxp3+ T cells became evident when contrasted with the ARDS model group (p < 0.0001) alongside the control (p < 0.001) (Figure 2). This evidence concerns the gene CD4 and acute respiratory distress syndrome.