The Eu-Myc;Id3+/− mice developed large abdominal tumours similar to the clinical presentation of sBL and had reduced latency to tumour development compared to Eu-Myc;Id3+/+ mice (median survival, 70.5 days and 114.0 days, respectively), suggestive that ID3 loss potentiated the effects of MYC in the pathogenesis of BL [7]. This evidence concerns the gene ID3 and neoplasm.