CXCR4 and myocardial infarction: Likewise, the HP of cardiac progenitor cells (CPCs) upregulated HIF-1α, C-X-C motif chemokine receptor 4 (CXCR4), and anti-apoptotic genes such as Bcl-2, significantly enhancing cell survival, homing to ischemic myocardium, and fibrotic remodelling after myocardial infarction via the stromal cell-derived factor 1-alpha (SDF-1α/CXCR4) axis [72].