The collapse of 2/3 of the quantified Complex 2 genes, critical for the Krebs cycle [64,65,66,67], in both untreated heart diseases investigated by us, resulted from the significant downregulation of Sdha (x(CCC) = −2.49, x(IHF) = −2.29) and Sdhb (x(CCC) = −2.07, x(IHF) = −1.59). This evidence concerns the gene SDHB and heart disorder.