MMP3 and lip and oral cavity carcinoma: For instance, a study by Monea et al. demonstrated the upregulation of MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-10, MMP-12, and MMP-13 in samples from oral cancer patients, with MMP-1, MMP-3, and MMP-9 identified as promising diagnostic biomarkers [65].