In a similar manner, no statistically significant difference in plasma zonulin level was observed between SLE patients with hypocomplementemia and those with normal serum complement values (n = 22, 7.257 ± 2.054 vs. n = 19, 7.924 ± 1.807, p = 0.613, Mann–Whitney U-test). The gene discussed is HP; the disease is systemic lupus erythematosus.