SERPINA7 and mucopolysaccharidosis type 4A: We previously reported that in models of MPS IVA, intravenous administration of an AAV8 vector encoding a human GALNS (hGALNS) under a liver-specific promoter (thyroxine-binding globulin [TBG]) resulted in supraphysiological enzyme levels in plasma and partial improvement of bone pathology [35].