CNPY3 and triple-negative breast carcinoma: Furthermore, high expression of CNPY3 and HSP90B1 correlated with poor differentiation (Figure 1B), PR negative status (Figure 1C), triple-negative breast cancer (TNBC) (Figure 1D), a high Nottingham Prognostic Index (NPI) (Figure 1E), and an aggressive basal subtype (Figure 1F).