Recent studies highlight specific CAF-derived factors that promote ovarian cancer progression, including non-canonical WNT5A signaling that sustains cancer stemness via the ROR2/PKC/CREB1 pathway [2], FGF7 (keratinocyte growth factor) that signals through FGFR2 to stabilize HIF‐1α and enhance proliferation, migration, and invasion [3], and stromal versican that cooperates with hyaluronan/CD44 to drive motility and peritoneal dissemination [4]. The gene discussed is WNT5A; the disease is ovarian cancer.