Single-cell RNA sequencing (scRNA-seq) data from lesional atopic dermatitis (AD) skin biopsies, as reported in a previously published study, were re-analyzed to assess the expression of 5-lipoxygenase (5-LO/ALOX5) and leukotriene-C4-synthase (LTC4S). Here, ALOX5 is linked to atopic eczema.