Analysis of single-cell RNA sequencing results in a data set obtained from lesional skin of AD patients of our previous publication [4] revealed higher expression of 5-LO/ALOX5 and LTC4S transcripts in monocytes and macrophages compared to other skin cells, with M1-like macrophages showing elevated 5-LO/ALOX5 transcript levels compared to M2-like macrophages. The gene discussed is LTC4S; the disease is Alzheimer disease.