Notably, the enrichment of the “Staphylococcus aureus infection” pathway in KEGG shares the core mechanism of “NF-κB-mediated inflammatory regulation” with E. faecalis infection [43], a finding that underscores a shared pathogenic strategy among enterococcal pathogens in modulating host inflammation. The gene discussed is NFKB1; the disease is staphylococcus aureus infection.