Notably, PG-1 treatment downregulated 6 genes ranking among the top 10 most upregulated genes following PCN033 infection, including C-X-C motif chemokine 9 (Cxcl9), C-X-C motif chemokine 11 (Cxcl11), Ubiquitin D (Ubd), Tumor necrosis factor receptor superfamily member 9 (Tnfrsf9), Vitamin D3 receptor (Vdr), and Receptor activity-modifying protein 3 (Ramp3). This evidence concerns the gene RAMP3 and infection.