Regarding E-cadherin expression, a high proportion of cases exhibited elevated staining scores (scores 3 and 4) in both metastatic tumors (56.52%, 13 cases) and non-metastatic tumors (43.48%, 4 cases), with no significant difference between the groups (p = 0.6989) (Table 3). This evidence concerns the gene CDH1 and metastatic neoplasm.