TTR and cardiomyopathy: Building on this foundation, Giadone et al. developed a large, ethnically diverse (including African American, Caucasian, and Asian populations) iPSC library from over 30 ATTR patients carrying TTR mutations such as Val30Met, Val122Ile, Leu55Pro, and Iso107Met, representing a range of clinical phenotypes including neuropathy and cardiomyopathy [69].