CASP8 and cancer: Based on Maximal Clique Centrality (MCC) scoring, the network prioritized 5 core metabolites (L-α-Glutamyl-L-Glutamic Acid, Maltitol, D-Maltose, Maltotriose, and Cytidine 5′-monophosphate), 5 pivotal targets (STAT3, HSP90AA1, CASP3, CASP8, and SRC), 3 disease modules (Infections, Neoplasms, Hyperphagia), and 2 key pathways (hsa05200: Pathways in cancer; hsa04217: Necroptosis).