In a randomized study, Obradovic et al. (2020) found that androgen deprivation therapy was associated with improved CD8+ T-cell infiltration within the prostate tumor microenvironment through increased expression of chemokines (including CXCL10 and IL7) and antigen presentation machinery (MHC class I and II) by tumor cells [44]. This evidence concerns the gene CD8A and prostate neoplasm.