After PSM (49 pairs) adjusting for gender, age, HCC etiology, EHS, maximal tumor size (≥8 cm), tumor number (≥10), major PVTT, Child–Pugh class, and AFP level (≥400 ng/mL), there was no survival difference between these two groups (18.8 vs. 12.0 months, p = 0.314) (Figure 6). This evidence concerns the gene AFP and hepatocellular carcinoma.