CD58 and anaplastic large cell lymphoma: Across T/NK cell lymphoma subtypes, CD58 expression is frequently lost, affecting >50% of cases in most PTCL categories, with the highest prevalence in ENKTL (83.3%), followed by PTCL-NOS (63.6%) and anaplastic large cell lymphoma (ALCL) (58%), underscoring its potential role in immune escape [10,18].