These phenotypes are associated with pathogenic variants in genes such as ABCA1, ABCG5, ALMS1, APOA1, APOA5, APOC2, APOC3, APOE, CREB3L3, GPIHBP1, LDLRAP1, LIPA, LMF1, and LPL, and are classified among the rare dyslipidemias frequently encountered in the monogenic dyslipidemia literature (e.g., EAS consensus) [8,9]. The gene discussed is APOA1; the disease is metabolic syndrome.